Structured illumination microscopy with a phase-modulated spinning disk for optical sectioning.
Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification.
Asghari, P., Scriven, D. R., Ng, M., Panwar, P., Chou, K. C., van Petegem, F., & Moore, E. D. eLife. 2020 January 9; 9
Single molecule localization deep within thick cells; a novel super-resolution microscope.
Tafteh, R., Scriven, D. R. L., Moore, E. D. W., & Chou, K. C.. Journal of Biophotonics. 2015 August 7; 9,1-2: 155-160.
Nonuniform and Variable Arrangements of Ryanodine Receptors Within Mammalian Ventricular Couplons
Asghari P, Scriven DRL, Sanatani S, Gandhi SK, Campbell AI and Moore ED. Circulation Res. 2014 July 7; 115: 252-262.
Microarchitecture of the Dyad
Scriven DR, Asghari P, and Moore ED. Cardiovascular Res. 2013 May 1; 98: 169-176.
Ca2 + channel and Na+/Ca2 + exchange localization in cardiac myocytes
Scriven DRL and Moore ED. J. Mol. Cell. Cardiol. 2013 May; 58:22-31. Epub 2012 Dec 7.
Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice
Bround MJ, Asghari P, Wambolt R, Bohunek L, Smits C, Philit M, Kieffer TJ, Lakatta EG, Boheler KR, Moore ED, Allard MF, and Johnson JD. Cardiovasc. Res. 2012 Dec 1; 96(3) : 372-380.
The structure and functioning of the couplon in the mammalian cardiomyocyte.
Asghari P, Scriven DR, Hoskins J, Fameli N, van Breemen C, and Moore ED. Protoplasma. 2011 Nov 5; 249: 31-38.
Couplons in rat atria form distinct subgroups defined by their molecular partners
Schulson MN, Scriven DRL, Fletcher P, and Moore ED. J. Cell Sci. 2011 Mar 8; 124(7): 1167-1174
Analysis of Cav1.2 and Ryanodine Receptor Clusters in Rat Ventricular Myocytes
Scriven DRL, Asghari P, Schulson MN and Moore ED. Biophys. J. 2010 Dec 15; 99(12): 3923-3929.
Multi-Image Colocalization and Its Statistical Significance
Fletcher PA, Scriven DRL, Schulson MN and Moore ED.
Biophys. J. 2010 Sep 22; 99(6): 1996-2005.
Integrin-mediated adhesion maintains sarcomeric integrity
Perkins AD, Ellis SJ, Asghari P, Shamsian A, Moore ED and Tanentzapf G.
Dev. Biol. 2010 Feb 1; 338(1): 15-27.
Axial Tubules of Rat Ventricular Myocytes Form Multiple Junctions with the Sarcoplasmic Reticulum
Asghari P, Schulson M, Scriven DRL, Martens G and Moore ED.
Biophysical J. 2009 June 3; 96(11): 4651-4660.
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation–contraction coupling, and cardiac arrhythmias
Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T,
Knollmann-Ritschel BEC, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C and Knollmann BC.
PNAS. 2009 May 5; 106: 7636-7641.
Image acquisition for colocalization using optical microscopy
Scriven DRL, Lynch RM and Moore ED.
Am J Physiol Cell Physiol. 2008 May; 294(5): C1119-1122.
Clearance of store-released Ca2+ by the Na+-Ca2+ exchanger is diminished in aortic smooth muscle from Na+-K+-ATPase α2-isoform gene-ablated mice
Lynch RM, Weber CS, Nullmeyer KD, Moore ED and Paul RJ.
Am J Physiol Heart Circ Physiol. 2008 Mar; 294(3): H1407-1416.
Subcellular characterization of glucose uptake in coronary endothelial cells
Gaudreault N, Scriven DRL, Laher I and Moore ED.
Microvascular Research. 2008 Jan; 75(1):73-82.
Localization of Kv1.5 channels in rat and canine myocyte sarcolemma
Eldstrom J, Van Wagoner DR, Moore ED and Fedida D.
FEBS Lett. 2006 Nov 13; 580(26): 6039-6046.
Asymmetric Subcellular Distribution of Glucose Transporters in the Endothelium of Small Contractile Arteries
Gaudreault N, Scriven DRL and Moore ED.
Endothelium. 2006 Sep-Oct; 13(5): 317-324.
Caveolin-3 is adjacent to a group of extradyadic ryanodine receptors.
Scriven DRL, Klimek A, Asghari P, Bellve K and Moore ED.
Biophys J. 2005 Sep; 89(3): 1893-1901.
Characterisation of glucose transporters in the intact coronary artery endothelium in rats: GLUT-2 upregulated by long-term hyperglycaemia
Gaudreault N, Scriven DRL and Moore ED.
Diabetologia. 2004 Dec; 47(12):2081-2092.
Organization of Ca2+ Release Units in Excitable Smooth Muscle of the Guinea-Pig Urinary Bladder
Moore ED, Voigt T, Kobayashi YM, Isenberg G, Fay FS, Gallitelli MF, Franzini-Armstrong C.
Biophys J. 2004 Sep;87(3): 1836-1847.
Helicobacter pylori infection targets adherens junction regulatory proteins and results in increased rates of migration in human gastric epithelial cells
Conlin VS, Curtis SB, Zhao Y, Moore ED, Smith VC, Meloche RM, Finlay BB, Buchan AM.
Infect Immun. 2004 Sep;72(9): 5181-5192.
Deconvolution of confocal images of dihydropyridine and ryanodine receptors in developing cardiomyocytes
Sedarat F, Lin E, Moore ED and Tibbits GF
J Appl Physiol. 2004 Sep;97(3): 1098-1103.
Increased focal Kv4.2 channel expression at the plasma membrane is the result of actin depolymerization
Wang Z, Eldstrom JR, Jantzi J, Moore ED and Fedida D.
Am J Physiol Heart Circ Physiol. 2004 Feb; 286(2): H749-759.
Epitope-dependent localization of estrogen receptor, but not -, in en face arterial endothelium
Dan P, Cheung JC, Scriven DRL and Moore ED.
Am J Physiol Heart Circ Physiol. 2003 Apr; 284(4): H1295-1306.
The Molecular Architecture of Calcium Microdomains in Rat Cardiomyocytes
Scriven DRL, Klimek A, Lee K and Moore ED.
Ann NY Acad Sci. 2002 Nov 1; 976: 488-499.
Pressure-dependent myogenic constriction of cerebral arteries occurs independently of voltage-dependent activation
Lagaud G, Gaudreault N, Moore ED, Van Breemen C and Laher I.
Am J Physiol Heart Circ Physiol. 2002 Aug 15; 283(6): H2187-2195.
Distribution of Proteins Implicated in Excitation-Contraction Coupling in Rat Ventricular Myocytes
Scriven DR, Dan P, Moore ED.
Biophys J. 2000 Nov 1; 79(5): 2682-2691.